发明授权
US06924358B2 121P1F1: a tissue specific protein highly expressed in various cancers
失效
121P1F1：在各种癌症中高度表达的组织特异性蛋白
- 专利标题： 121P1F1: a tissue specific protein highly expressed in various cancers
- 专利标题（中）： 121P1F1：在各种癌症中高度表达的组织特异性蛋白
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申请号： US09799250申请日： 2001-03-05
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公开(公告)号： US06924358B2公开(公告)日： 2005-08-02
- 发明人: Pia M. Challita-Eid , Rene S. Hubert , Steve Chappell Mitchell , Arthur B. Raitano , Mary Faris , Daniel E. H. Afar , Aya Jakobovits
- 申请人： Pia M. Challita-Eid , Rene S. Hubert , Steve Chappell Mitchell , Arthur B. Raitano , Mary Faris , Daniel E. H. Afar , Aya Jakobovits
- 申请人地址： US CA Santa Monica
- 专利权人： Agensys, Inc.
- 当前专利权人： Agensys, Inc.
- 当前专利权人地址： US CA Santa Monica
- 代理机构： Morrison & Foerster LLP
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07K14/47 ; G01N33/574 ; A61K33/00 ; C07K1/00 ; C07H21/04
摘要：
A novel gene (designated 121P1F1) and its encoded protein are described. While 121P1F1 exhibits tissue specific expression in normal adult tissue, it is aberrantly expressed in multiple cancers including prostate, bladder, kidney, brain, bone, cervical, uterine, ovarian, breast, pancreatic, stomach, colon, rectal, leukocytic, liver and lung cancers. Consequently, 121P1F1 provides a diagnostic and/or therapeutic target for cancers, and the 121P1F1 gene or fragment thereof, or its encoded protein or a fragment thereof used to elicit an immune response.