Invention Grant
- Patent Title: Secreted and transmembrane polypeptides and nucleic acids encoding the same
- Patent Title (中): 分泌和跨膜多肽和编码其的核酸
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Application No.: US09944944Application Date: 2001-08-31
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Publication No.: US06929947B2Publication Date: 2005-08-16
- Inventor: David Botstein , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Margaret Ann Roy , William I. Wood
- Applicant: David Botstein , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Margaret Ann Roy , William I. Wood
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Brinks Hofer Gilson & Lione
- Agent Elizabeth M. Barnes; Mark T. Kresnak
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C07K14/47 ; C12N5/06 ; C12N9/00

Abstract:
The present invention is directed to nucleic acids encoding a secreted polypeptide that inhibits neoplastic growth in tumor cells. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Public/Granted literature
- US20020173463A1 Secreted and transmembrane polypeptides and nucleic acids encoding the same Public/Granted day:2002-11-21
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