发明授权
- 专利标题: Use of 2-alkoxyphenol-substituted imidazotriazinones
- 专利标题(中): 使用2-烷氧基苯酚取代的咪唑并三嗪酮
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申请号: US10483462申请日: 2002-07-17
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公开(公告)号: US06930108B2公开(公告)日: 2005-08-16
- 发明人: Ulrich Niewöhner
- 申请人: Maria Theresia Niewöhner , Erwin Bischoff , Helmut Haning , Afssaneh Rahbar , Tiemo-Joerg Bandel , Wolfgang Barth
- 申请人地址: DE Leverkusen
- 专利权人: Bayer HealthCare AG
- 当前专利权人: Bayer HealthCare AG
- 当前专利权人地址: DE Leverkusen
- 代理商 Susan M. Pellegrino
- 优先权: DE10135815 20010723
- 国际申请: PCT/EP02/07959 WO 20020717
- 国际公布: WO03/01126 WO 20030213
- 主分类号: C07D487/04
- IPC分类号: C07D487/04 ; A61K31/00 ; A61K31/53 ; A61K31/5377 ; A61K31/675 ; A61P1/00 ; A61P3/10 ; A61P9/04 ; A61P9/12 ; A61P11/00 ; A61P11/12 ; A61P13/08 ; A61P13/10 ; A61P13/12 ; A61P15/00 ; A61P15/06 ; A61P15/08 ; A61P17/06 ; A61P17/14 ; A61P23/00 ; A61P25/04 ; A61P25/16 ; A61P27/06 ; A61P27/16 ; A61P35/00 ; C07D519/00
摘要:
The present invention relates to the use of known 2-phenyl-substituted imidazotriazinones having short, unbranched alkyl radicals in the 9-position and cGMP PDE-inhibitory properties for the production of medicaments for the treatment of cardiac insufficiency, psoriasis, female infertility, cancer, diabetes, ophthalmic disorders such as glaucoma, disorders of gastric motility, cystic fibrosis, premature labour, pulmonary hypertension, bladder disorders, prostate hyperplasia, nitrate-induced tolerance, pre-eclampsia, alopecia, Parkinson's disease, pain, tinnitus or the renal syndrome.
公开/授权文献
- US20040235838A1 Use of 2-alkoxyphenol-substituted imidazotriazinones 公开/授权日:2004-11-25
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