发明授权
- 专利标题: Citrullimycines, a process for their production and their use as pharmaceuticals
- 专利标题(中): 柑橘霉素,其生产过程及其作为药物的使用
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申请号: US09966109申请日: 2001-10-01
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公开(公告)号: US06930130B2公开(公告)日: 2005-08-16
- 发明人: Cordula Hopmann , Michael Kurz , Mark Brönstrup , Joachim Wink
- 申请人: Cordula Hopmann , Michael Kurz , Mark Brönstrup , Joachim Wink
- 申请人地址: DE Frankfurt am Main
- 专利权人: Aventis Pharma Deutschland GmbH
- 当前专利权人: Aventis Pharma Deutschland GmbH
- 当前专利权人地址: DE Frankfurt am Main
- 代理机构: Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
- 优先权: EP00121566 20001002
- 主分类号: C12P41/00
- IPC分类号: C12P41/00 ; A61K31/17 ; A61K31/197 ; A61K31/22 ; A61K31/223 ; A61P25/16 ; A61P25/18 ; A61P25/28 ; A61P43/00 ; C07C275/16 ; C12N1/20 ; C12P13/00 ; C12P13/10 ; C12R1/465 ; A61K31/13 ; C07D211/70 ; C12N1/00
摘要:
The present invention relates to novel active compounds named Citrullimycines, which are obtainable by cultivation of Streptomyces sp. ST 101396 (DSM 13309), and to their pharmaceutically acceptable salts and derivatives. The present invention further relates to a process for the production of the Citrullimycines, to the microorganism Streptomycetes sp. ST 101396 (DSM 13309), to the use of the Citrullimycines and their pharmaceutically acceptable salts and derivatives as pharmaceuticals, for example as inhibitors of the neurotensin receptor, and to pharmaceutical compositions comprising Citrullimycines or a pharmaceutically acceptable salt or derivative thereof.