发明授权
US06936466B2 Transcriptionally-activated AAV inverted terminal repeats (ITRs) for use with recombinant AAV vectors
失效
转录激活的AAV反向末端重复(ITR),用于重组AAV载体
- 专利标题: Transcriptionally-activated AAV inverted terminal repeats (ITRs) for use with recombinant AAV vectors
- 专利标题(中): 转录激活的AAV反向末端重复(ITR),用于重组AAV载体
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申请号: US09909363申请日: 2001-07-19
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公开(公告)号: US06936466B2公开(公告)日: 2005-08-30
- 发明人: Andrew L. Feldhaus
- 申请人: Andrew L. Feldhaus
- 申请人地址: US WA Seattle
- 专利权人: Targeted Genetics Corporation
- 当前专利权人: Targeted Genetics Corporation
- 当前专利权人地址: US WA Seattle
- 代理机构: Morrison & Foerster LLP
- 主分类号: A61K48/00
- IPC分类号: A61K48/00 ; C07K14/47 ; C12N7/01 ; C12N15/864 ; C12N15/84 ; C12N5/10
摘要:
This invention provides transcriptionally-activated AAV ITRs (inverted terminal repeats) which are small and transcriptionally active and uses thereof to optimize the expression of relatively large transgenes packaged in recombinant AAV vectors.
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