A growth factor delivery system for use in connection with microdermabrasion includes a source of growth factors. The growth material may be dry and thus mixed in with the abrasion media. The dry growth material would therefore be applied to the target skin area simultaneously with the abrasion media by a single handpiece. The growth material may comprise a fluid to be delivered by a separate handpiece. The fluid source may be within the handpiece or external thereto. The fluid source may be contained in a removable cartridge adapted to fit within the handpiece. Thus, a method and system is provided for using disposable cartridges of growth fluids.