发明授权
- 专利标题: Guanidinomethyl cyclohexane carboxylic acid ester derivatives
- 专利标题(中): 胍基甲基环己烷羧酸酯衍生物
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申请号: US10623135申请日: 2003-07-18
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公开(公告)号: US06960681B2公开(公告)日: 2005-11-01
- 发明人: Osamu Kamoda , Hiromichi Fujiwara , Toshiharu Yanagi
- 申请人: Osamu Kamoda , Hiromichi Fujiwara , Toshiharu Yanagi
- 申请人地址: JP Osaka
- 专利权人: Nagase ChemteX Corporation
- 当前专利权人: Nagase ChemteX Corporation
- 当前专利权人地址: JP Osaka
- 代理机构: Edwards & Angell, LLP
- 代理商 Peter F. Corless; John B. Alexander
- 优先权: JP6-243489 19940830; JP6-243490 19940830; JP6-248270 19940905; JP6-252655 19940909
- 主分类号: A61K31/215
- IPC分类号: A61K31/215 ; A61K31/24 ; C07C69/94 ; C07C279/14 ; C07C69/76
摘要:
The invention relates to novel and valuable intermediate compounds of the general formula (VIII) which can be used for the preparation of novel compounds comprising an antibacterial action, especially with a strong antibacterial action against helicobacter pylori, and pharmaceutically acceptable salts thereof. In the general formula (VIII) X is hydrogen or halogen, Y is hydrogen or a substituted or unsubstituted aralkyloxycarbonyl group having 8-19 carbon atoms, Z is hydrogen, a substituted aralkyloxycarbonyl group having 8-19 carbon atoms or a substituted alkoxycarbonyyl group having 2-19 carbon atoms, except that X, Y and Z are all hydrogen.
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