发明授权
- 专利标题: Method for the treatment or prevention of viral infection using nucleoside analogues
- 专利标题(中): 使用核苷类似物治疗或预防病毒感染的方法
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申请号: US10401727申请日: 2003-03-31
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公开(公告)号: US06964968B2公开(公告)日: 2005-11-15
- 发明人: Francis J. Giles , Jean Bédard , Robert F. Rando
- 申请人: Francis J. Giles , Jean Bédard , Robert F. Rando
- 申请人地址: CA Ville Saint-Laurent
- 专利权人: Shire Biochem, Inc.
- 当前专利权人: Shire Biochem, Inc.
- 当前专利权人地址: CA Ville Saint-Laurent
- 代理机构: Millen, White, Zelano, Branigan, P.C.
- 主分类号: C07D405/04
- IPC分类号: C07D405/04 ; A61K31/506 ; A61K31/513 ; A61K31/522 ; A61K31/53 ; A61K31/662 ; A61K31/7052 ; A61K31/7072 ; A61K45/00 ; A61K45/06 ; A61K48/00 ; A61P31/12 ; A01N43/54 ; A01N43/90 ; A61K31/505 ; A61K31/52
摘要:
Viral infections selected from the group consisting of herpes simplex virus, varicella zoster virus, respiratory syncytial virus and cytomegalovirus can be treated by administering to the host a therapeutically effective amount of a compound of formula I or a pharmaceutically acceptable salt thereof; wherein Y, Ra, and R1 are as defined herein. The compounds and salts can also be used to inhibit viral replication of these viruses in cells.
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