Invention Grant
US06966992B2 Method of purification of molecules using unbranched terminal alkyldiols
有权
使用无支链末端烷基二醇纯化分子的方法
- Patent Title: Method of purification of molecules using unbranched terminal alkyldiols
- Patent Title (中): 使用无支链末端烷基二醇纯化分子的方法
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Application No.: US09813093Application Date: 2001-03-19
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Publication No.: US06966992B2Publication Date: 2005-11-22
- Inventor: Terry Allen Hauser , Kirk James Hayenga
- Applicant: Terry Allen Hauser , Kirk James Hayenga
- Applicant Address: NL Arnhem
- Assignee: Akzo Nobel NV
- Current Assignee: Akzo Nobel NV
- Current Assignee Address: NL Arnhem
- Agent William P. Ramey, III
- Main IPC: B01D15/32
- IPC: B01D15/32 ; B01D15/42 ; C07K1/20 ; C07K14/61 ; C07K14/655 ; C07K14/685 ; C07K14/70 ; B01D15/08
Abstract:
The current invention provides methods for molecule purification by RP-LC and RP-HPLC that uses unbranched terminal alkyldiols as eluting solvents. In particular, the present invention purifies molecules, particularly proteins and peptides, on reverse phase liquid chromatography columns using a buffer containing either 1,5 pentanediol, 1,6 hexanediol or 1,7 heptanediol.
Public/Granted literature
- US20020183483A1 Method for purification of molecules using unbranched terminal alkyldiols Public/Granted day:2002-12-05
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