发明授权
US06966992B2 Method of purification of molecules using unbranched terminal alkyldiols
有权
使用无支链末端烷基二醇纯化分子的方法
- 专利标题: Method of purification of molecules using unbranched terminal alkyldiols
- 专利标题(中): 使用无支链末端烷基二醇纯化分子的方法
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申请号: US09813093申请日: 2001-03-19
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公开(公告)号: US06966992B2公开(公告)日: 2005-11-22
- 发明人: Terry Allen Hauser , Kirk James Hayenga
- 申请人: Terry Allen Hauser , Kirk James Hayenga
- 申请人地址: NL Arnhem
- 专利权人: Akzo Nobel NV
- 当前专利权人: Akzo Nobel NV
- 当前专利权人地址: NL Arnhem
- 代理商 William P. Ramey, III
- 主分类号: B01D15/32
- IPC分类号: B01D15/32 ; B01D15/42 ; C07K1/20 ; C07K14/61 ; C07K14/655 ; C07K14/685 ; C07K14/70 ; B01D15/08
摘要:
The current invention provides methods for molecule purification by RP-LC and RP-HPLC that uses unbranched terminal alkyldiols as eluting solvents. In particular, the present invention purifies molecules, particularly proteins and peptides, on reverse phase liquid chromatography columns using a buffer containing either 1,5 pentanediol, 1,6 hexanediol or 1,7 heptanediol.
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