发明授权
- 专利标题： OAT5 molecules and uses therefor
- 专利标题（中）： OAT5分子及其用途
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申请号： US10154419申请日： 2002-05-22
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公开(公告)号： US06972187B2公开(公告)日： 2005-12-06
- 发明人: Rory A. J. Curtis , Maria Alexandra Glucksmann , Rachel E. Meyers
- 申请人： Rory A. J. Curtis , Maria Alexandra Glucksmann , Rachel E. Meyers
- 申请人地址： US MA Cambridge
- 专利权人： Millennium Pharmaceuticals, Inc.
- 当前专利权人： Millennium Pharmaceuticals, Inc.
- 当前专利权人地址： US MA Cambridge
- 代理机构： Millennium Pharmaceuticals, Inc.
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K48/00 ; C07K14/47 ; C07K14/705 ; C12N9/14 ; C12N9/16 ; G01N33/50 ; G01N33/68 ; C12N15/00 ; C07H21/04 ; C12N1/21 ; C12N15/63 ; C12N15/85
摘要：
The invention provides isolated nucleic acids molecules, designated OAT5 nucleic acid molecules, which encode organic anion transporters. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing OAT5 nucleic acid molecules, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a OAT5 gene has been introduced or disrupted. The invention still further provides isolated OAT5 polypeptides, fusion polypeptides, antigenic peptides and anti-OAT5 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
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