发明授权
US06979740B2 Process for preparation of ring-substituted 8-aminoquinoline analogs as antimalarial agents
有权
制备环取代的8-氨基喹啉类似物作为抗疟剂的方法
- 专利标题： Process for preparation of ring-substituted 8-aminoquinoline analogs as antimalarial agents
- 专利标题（中）： 制备环取代的8-氨基喹啉类似物作为抗疟剂的方法
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申请号： US10737589申请日： 2003-12-15
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公开(公告)号： US06979740B2公开(公告)日： 2005-12-27
- 发明人: Rahul Jain , Meenakshi Jain , Prati Pal Singh , Sacita Singh , Sandeep Sachdeva , Vijai Misra , Poduri Ramarao , Chaman Lal Kaul , Kulbhushan Tikoo
- 申请人： Rahul Jain , Meenakshi Jain , Prati Pal Singh , Sacita Singh , Sandeep Sachdeva , Vijai Misra , Poduri Ramarao , Chaman Lal Kaul , Kulbhushan Tikoo
- 申请人地址： IN Punjab
- 专利权人： National Institute of Pharmaceutical Education and Research
- 当前专利权人： National Institute of Pharmaceutical Education and Research
- 当前专利权人地址： IN Punjab
- 代理机构： Rutan & Tucker, LLP
- 优先权： IN472/DEL/2003 20030327; IN459/DEL/2003 20030327
- 主分类号： C07D215/40
- IPC分类号： C07D215/40 ; C07D215/38 ; A61K31/47
摘要：
The present invention is concerned with the development of novel 8-aminoquinoline analogs in the treatment and prevention of malaria and the said compound has broad spectrum of activity against the blood as well as tissue stages of the human malaria parasites makes these compounds very attractive in the cure and prevention of malaria caused by drug-sensitive and multidrug resistant strains and also it is expected that development of these compounds as ideal antimalarial agents may lead to suppression as well as radical cure of the malaria infection with single drug therapy.
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