发明授权
- 专利标题： Device for taking measurements of cells which are contained in a liquid environment
- 专利标题（中）： 用于测量包含在液体环境中的细胞的装置
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申请号： US10302163申请日： 2002-11-20
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公开(公告)号： US06984297B2公开(公告)日： 2006-01-10
- 发明人: Wilfried Nisch , Martin Stelzle , Alfred Stett , Thomas Krahn , Thomas Müller , Christoph Methfessel
- 申请人： Wilfried Nisch , Martin Stelzle , Alfred Stett , Thomas Krahn , Thomas Müller , Christoph Methfessel
- 申请人地址： DE Reutlingen DE Leverkusen
- 专利权人： NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen,Bayer AG
- 当前专利权人： NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen,Bayer AG
- 当前专利权人地址： DE Reutlingen DE Leverkusen
- 代理机构： Knobbe, Martens, Olson & Bear LLP
- 优先权： DE19948473 19991008
- 主分类号： C12N9/00
- IPC分类号： C12N9/00 ; C25B11/08 ; C12Q1/02 ; C12M1/40 ; A61B5/04
摘要：
A method and a device are used for carrying out measurements on cells located in a liquid environment. Each cell is positioned with an underside of its membrane on a surface having a channel running through it. A negative pressure is established to aspirate the cells. Each cell is electrically scanned via at least one electrode which is spaced apart from the cell. The negative pressure is preferably established in a pulse-like manner to rupture the membrane in such a way that the cell interior enclosed by the membrane is connected to the channel.
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