发明授权
US06984645B2 Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein
有权
脂肪细胞脂肪酸结合蛋白和角质形成细胞脂肪酸结合蛋白的双重抑制剂
- 专利标题： Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein
- 专利标题（中）： 脂肪细胞脂肪酸结合蛋白和角质形成细胞脂肪酸结合蛋白的双重抑制剂
-
申请号： US10295819申请日： 2002-11-15
-
公开(公告)号： US06984645B2公开(公告)日： 2006-01-10
- 发明人: David R. Magnin , Richard B. Sulsky , Jeffrey A. Robl , Thomas J. Caulfield , Rex A. Parker
- 申请人： David R. Magnin , Richard B. Sulsky , Jeffrey A. Robl , Thomas J. Caulfield , Rex A. Parker
- 申请人地址： US NJ Princeton
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 当前专利权人地址： US NJ Princeton
- 代理商 Joseph C. Wang; Laurelee A. Duncan
- 主分类号： A61K31/435
- IPC分类号： A61K31/435 ; A61K31/19 ; A61K31/195 ; C07D233/54 ; C07D65/03
摘要：
Compounds that are dual aP2/k-FABP inhibitors are provided having the formula wherein A, B, X, Y, R1, R2 and R3 are as described herein. A method is also provided for treating diabetes and related diseases, especially Type II diabetes, employing dual aP2/k-FABP inhibitors alone or in combination with at least one other antidiabetic agent such as metformin, glyburide, troglitazone and/or insulin.
公开/授权文献
信息查询
