- 专利标题: Methods of diagnosing liver fibrosis
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申请号: US10087188申请日: 2002-02-28
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公开(公告)号: US06986995B2公开(公告)日: 2006-01-17
- 发明人: Steven L. Rose , Esther H. Oh , Michael J. Walsh
- 申请人: Steven L. Rose , Esther H. Oh , Michael J. Walsh
- 申请人地址: US CA San Diego
- 专利权人: Prometheus Laboratories, Inc.
- 当前专利权人: Prometheus Laboratories, Inc.
- 当前专利权人地址: US CA San Diego
- 代理机构: Townsend and Townsend and Crew LLP
- 主分类号: C12Q1/37
- IPC分类号: C12Q1/37 ; G01N33/576 ; G01N33/68
摘要:
The present invention provides a method of diagnosing the presence or severity of liver fibrosis in an individual by detecting α2-macroglobulin (α2-MG) in a sample from the individual; detecting hyaluronic acid (HA) in a sample from the individual; detecting tissue inhibitor of metalloproteinases-1 (TIMP-1) in a sample from the individual; and diagnosing the presence or severity of liver fibrosis in the individual based on the presence or level of α2-MG, HA and TIMP-1.
公开/授权文献
- US20030175686A1 Methods of diagnosing liver fibrosis 公开/授权日:2003-09-18
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