发明授权
US06987106B1 1,4-diazabicyclo[3.2.2]nonane-4-carboxylates and carboxamide derivates, production and use thereof in therapeutics
有权
1,4-二氮杂双环[3.2.2]壬烷-4-羧酸酯和羧酰胺衍生物,其在治疗中的生产和应用
- 专利标题: 1,4-diazabicyclo[3.2.2]nonane-4-carboxylates and carboxamide derivates, production and use thereof in therapeutics
- 专利标题(中): 1,4-二氮杂双环[3.2.2]壬烷-4-羧酸酯和羧酰胺衍生物,其在治疗中的生产和应用
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申请号: US09937045申请日: 2000-03-21
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公开(公告)号: US06987106B1公开(公告)日: 2006-01-17
- 发明人: Thierry Gallet , Samir Jegham , Patrick Lardenois , Alistair Lochead , Alain Nedelec
- 申请人: Thierry Gallet , Samir Jegham , Patrick Lardenois , Alistair Lochead , Alain Nedelec
- 申请人地址: FR Paris
- 专利权人: Sanofi-Aventis
- 当前专利权人: Sanofi-Aventis
- 当前专利权人地址: FR Paris
- 代理商 Balaram Gupta
- 优先权: FR9903934 19990330
- 国际申请: PCT/FR00/00697 WO 20000321
- 国际公布: WO00/58311 WO 20001005
- 主分类号: A61P25/00
- IPC分类号: A61P25/00 ; A61K31/551 ; C07D471/08
摘要:
Compounds of general formula in which X represents an oxygen atom or a group of formula NZ in which Z represents a hydrogen atom or an alkyl group, n represents a number 0, 1 or 2, and R1, R2, R3, R4 and R5 each represent a hydrogen or halogen atom or a trifluoromethyl, trifluoromethoxy, cyano, hydroxyl, alkyl, alkoxy, phenoxy or phenyl group optionally substituted with a halogen atom or a trifluoromethyl, cyano, hydroxyl, alkyl or alkoxy group, or alternatively R2 and R3 together form a group of formula —OCH2O— or —CH2CH2CH2CH2—. Application in therapy.
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