Methods of performing dyadic digital signal processing (DSP) instructions. In one embodiment of the invention, the method includes fetching a dyadic DSP instruction having a main operation and a sub operation; predecoding the dyadic DSP instruction to generate predecoded instruction signals; and decoding the predecoded instruction signals to generate select signals to selectively couple data from a first plurality of buses coupled to inputs of multiplexers of a first plurality of DSP functional blocks to execute the main operation of the dyadic DSP instruction in one processor cycle and to selectively couple data from a second plurality of buses coupled to inputs of multiplexers of a second plurality of DSP functional blocks to execute the sub operation of the dyadic DSP instruction in the one processor cycle.