- 专利标题： Thiol-based NAALADase inhibitors
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申请号： US10959199申请日： 2004-10-07
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公开(公告)号： US06992215B2公开(公告)日： 2006-01-31
- 发明人: Takashi Tsukamoto , Pavel Majer , Doris Stoermer , Barbara S. Slusher
- 申请人： Takashi Tsukamoto , Pavel Majer , Doris Stoermer , Barbara S. Slusher
- 申请人地址： US MD Baltimore
- 专利权人： Guildford Pharmaceuticals Inc.
- 当前专利权人： Guildford Pharmaceuticals Inc.
- 当前专利权人地址： US MD Baltimore
- 代理机构： Foley & Lardner, LLP
- 主分类号： C07C321/06
- IPC分类号： C07C321/06 ; C07C323/04 ; C07C317/14 ; A61K31/095
摘要：
This invention relates to new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, effecting neuronal activity, effecting TGF-β activity, inhibiting angiogenesis, and treating glutamate abnormalities, diabetic neuropathy, pain, compulsive disorders, prostate diseases, cancers and glaucoma.
公开/授权文献
- US20050085503A1 Thiol-based NAALADase inhibitors 公开/授权日：2005-04-21
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