发明授权
US06995243B2 Antibodies that recognize and bind phosphorylated human glucocorticoid receptor and methods of using same
有权
识别和结合磷酸化人类糖皮质激素受体的抗体及其使用方法
- 专利标题： Antibodies that recognize and bind phosphorylated human glucocorticoid receptor and methods of using same
- 专利标题（中）： 识别和结合磷酸化人类糖皮质激素受体的抗体及其使用方法
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申请号： US10629913申请日： 2003-07-30
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公开(公告)号： US06995243B2公开(公告)日： 2006-02-07
- 发明人: Michael Garabedian , Zhen Wang
- 申请人： Michael Garabedian , Zhen Wang
- 申请人地址： US NY New York
- 专利权人： New York University
- 当前专利权人： New York University
- 当前专利权人地址： US NY New York
- 代理机构： Browdy and Neimark, PLLC
- 主分类号： C07K16/00
- IPC分类号： C07K16/00 ; C07K16/18 ; C07K16/28 ; G01N33/53 ; G01N33/68
摘要：
A molecule containing the antigen binding portion of an antibody specific for human glucocorticoid receptor phosphorylated at residue Ser211, Ser226 or Ser203 is obtained and a method of determining the presence of activated glucocorticoid receptors in cells from human glucocorticoid responsive tissue and a method of screening for a glucocorticoid agonist using the molecule, which is preferably an antibody, are provided in the present invention.
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