发明授权
US06995254B1 Polynucleotide encoding the enoyl-acyl carrier protein reductase of Staphylococcus aureus, FAB I
失效
编码金黄色葡萄球菌的烯酰基酰基载体蛋白还原酶的多核苷酸，FAB I
- 专利标题： Polynucleotide encoding the enoyl-acyl carrier protein reductase of Staphylococcus aureus, FAB I
- 专利标题（中）： 编码金黄色葡萄球菌的烯酰基酰基载体蛋白还原酶的多核苷酸，FAB I
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申请号： US08790043申请日： 1997-01-28
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公开(公告)号： US06995254B1公开(公告)日： 2006-02-07
- 发明人: David John Payne , Peter Henry Milner , Stewart Campbell Pearson , John Timothy Lonsdale
- 申请人： David John Payne , Peter Henry Milner , Stewart Campbell Pearson , John Timothy Lonsdale
- 申请人地址： CA Toronto
- 专利权人： Affinium Pharmaceuticals, Inc.
- 当前专利权人： Affinium Pharmaceuticals, Inc.
- 当前专利权人地址： CA Toronto
- 代理机构： Foley Hoag, LLP
- 主分类号： C07H21/00
- IPC分类号： C07H21/00 ; C12N15/31 ; C12N15/53
摘要：
Prokayrotic FAB I polypeptides and DNA (RNA) encoding such FAB I and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such FAB I for the treatment of infection, such as bacterial infections. Antagonists against such FAB I and their use as a therapeutic to treat infections, such as staphylococcal infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of FAB I nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding FAB I and for detecting the polypeptide in a host.
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