发明授权
- 专利标题： Process for synthesis of bead-shaped cross-linked hydrophilic support polymer
- 专利标题（中）： 珠状交联亲水载体聚合物的合成方法
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申请号： US09600180申请日： 1999-02-01
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公开(公告)号： US07011963B1公开(公告)日： 2006-03-14
- 发明人: Christian Meier , Thomas Suefke , Hans-Ulrich Petereit , Roger Recktenwald , Thomas Boller
- 申请人： Christian Meier , Thomas Suefke , Hans-Ulrich Petereit , Roger Recktenwald , Thomas Boller
- 申请人地址： DE Darmstadt
- 专利权人： Roehm GmbH & Co KG
- 当前专利权人： Roehm GmbH & Co KG
- 当前专利权人地址： DE Darmstadt
- 代理机构： Oblon, Spivak, McClelland, Maier & Neustadt, P.C.
- 优先权： DE19804518 19980205
- 国际申请： PCT/EP99/00635 WO 19990201
- 国际公布： WO99/40122 WO 19990812
- 主分类号： C12N11/08
- IPC分类号： C12N11/08 ; C12P1/00 ; G01N33/545 ; C07K17/08 ; A61K9/14
摘要：
The invention relates to a process for synthesis, by inverse bead polymerization of a monomer phase, of a bead-like, cross-linked, hydrophilic copolymer which has binding activity toward ligands containing nucleophilic groups. The invention relates to support polymer materials with high binding capacity for penicillin acylase and low swelling factor, as well as to use of the same.
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