发明授权
- 专利标题： Nucleic acids encoding secreted polypeptides that stimulate release of proteoglycans from cartilage
- 专利标题（中）： 编码分泌的多肽的核酸，其刺激蛋白聚糖从软骨释放
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申请号： US09944884申请日： 2001-08-31
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公开(公告)号： US07018837B2公开(公告)日： 2006-03-28
- 发明人: Kevin P. Baker , David Botstein , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Mary A. Napier , Margaret Ann Roy , Daniel Tumas , William I. Wood
- 申请人： Kevin P. Baker , David Botstein , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Mary A. Napier , Margaret Ann Roy , Daniel Tumas , William I. Wood
- 申请人地址： US CA South San Francisco
- 专利权人： Genentech, Inc.
- 当前专利权人： Genentech, Inc.
- 当前专利权人地址： US CA South San Francisco
- 代理机构： Brinks Hofer Gilson & Lione
- 代理商 Mark T. Kresnak; Elizabeth M. Barnes
- 主分类号： C12N15/85
- IPC分类号： C12N15/85 ; C12N1/21 ; C12N1/19 ; C12N15/63 ; C07H21/04
摘要：
The present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.