发明授权
- 专利标题: Pyrrolidine sulfonamides
- 专利标题(中): 吡咯烷磺酰胺
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申请号: US11119026申请日: 2005-04-29
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公开(公告)号: US07019008B2公开(公告)日: 2006-03-28
- 发明人: Dashyant Dhanak , Steven D. Knight , Jian Jin , Ralph A. Rivero , Anthony Sapienza
- 申请人: Dashyant Dhanak , Steven D. Knight , Jian Jin , Ralph A. Rivero , Anthony Sapienza
- 申请人地址: US PA Philadelphia
- 专利权人: SmithKline Beecham Corporation
- 当前专利权人: SmithKline Beecham Corporation
- 当前专利权人地址: US PA Philadelphia
- 代理商 Andrea V. Lockenour; Linda Hall; Edward R. Gimmi
- 主分类号: A61K31/496
- IPC分类号: A61K31/496 ; C07D409/14
摘要:
A compound of Formula (I): wherein: R1 is C1-6 alkyl, benzyl, or (CH2)n—C(O)NH2; wherein the benzyl may be unsubstituted or substituted by one or two C1-6 alkyl, halogen, C1-6 alkoxy, or methylenedioxy groups; R2 is benzimidazolyl, quinolinyl, benzofuranyl, napthyl, indolyl, benzothiophenyl, phenyl, furanyl, thienyl, or pyridyl substituted or unsubstituted by one, two or three halogen, C1-3 alkyl, C1-3 alkoxy, or methylenedioxy groups; X1 and X2 are independently hydrogen, halogen, C1-3 alkyl, C1-3 alkoxy, nitro, CF3, or CN; n is 1, 2, or 3; m is 1, 2 or 3; or a pharmaceutically acceptable salt thereof.
公开/授权文献
- US20050197345A1 Pyrrolidine sulfonamides 公开/授权日:2005-09-08
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