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    Pyrrolidine sulfonamides
    1.
    发明授权
    Pyrrolidine sulfonamides 失效
    吡咯烷磺酰胺

    公开(公告)号：US07019008B2

    公开(公告)日：2006-03-28

    申请号：US11119026

    申请日：2005-04-29

    申请人： Dashyant Dhanak ,  Steven D. Knight ,  Jian Jin ,  Ralph A. Rivero ,  Anthony Sapienza

    发明人： Dashyant Dhanak ,  Steven D. Knight ,  Jian Jin ,  Ralph A. Rivero ,  Anthony Sapienza

    IPC分类号： A61K31/496 ,  C07D409/14

    CPC分类号： C07D409/12

    摘要： A compound of Formula (I): wherein: R1 is C1-6 alkyl, benzyl, or (CH2)n—C(O)NH2; wherein the benzyl may be unsubstituted or substituted by one or two C1-6 alkyl, halogen, C1-6 alkoxy, or methylenedioxy groups; R2 is benzimidazolyl, quinolinyl, benzofuranyl, napthyl, indolyl, benzothiophenyl, phenyl, furanyl, thienyl, or pyridyl substituted or unsubstituted by one, two or three halogen, C1-3 alkyl, C1-3 alkoxy, or methylenedioxy groups; X1 and X2 are independently hydrogen, halogen, C1-3 alkyl, C1-3 alkoxy, nitro, CF3, or CN; n is 1, 2, or 3; m is 1, 2 or 3; or a pharmaceutically acceptable salt thereof.

    摘要翻译： 式（I）的化合物：其中：R 1是C 1-6烷基，苄基或（CH 2 CH 2） -C（O）NH 2; 其中苄基可以是未取代的或被一个或两个C 1-6烷基，卤素，C 1-6烷氧基或亚甲二氧基取代; R 2是苯并咪唑基，喹啉基，苯并呋喃基，萘基，吲哚基，苯并噻吩基，苯基，呋喃基，噻吩基或被1,2或3个卤素取代或未取代的吡啶基， 亚烷基，C 1-3烷氧基或亚甲二氧基; X 1和X 2独立地是氢，卤素，C 1-3烷基，C 1-3烷氧基 ，硝基，CF 3或CN; n为1,2或3; m为1,2或3; 或其药学上可接受的盐。

    Scalable intra-panel interface
    8.
    发明授权
    Scalable intra-panel interface 有权
    可扩展的面板内接口

    公开(公告)号：US09053673B2

    公开(公告)日：2015-06-09

    申请号：US13070416

    申请日：2011-03-23

    申请人： Zhengyu Yuan ,  Jian Jin ,  Ming Qu ,  Ding Lu ,  Zhanpeng Zhang ,  Qing Ouyang

    发明人： Zhengyu Yuan ,  Jian Jin ,  Ming Qu ,  Ding Lu ,  Zhanpeng Zhang ,  Qing Ouyang

    IPC分类号： G06F3/038 ,  G09G3/36 ,  G09G3/20

    CPC分类号： G09G3/3611 ,  G09G3/20 ,  G09G2300/0426 ,  G09G2310/027 ,  G09G2330/06 ,  G09G2330/12 ,  G09G2352/00 ,  G09G2370/08 ,  G09G2370/14

    摘要： A system and a method are disclosed for an intra-panel communication interface which, among other advantages, enhances system reliability and reduces bus width. A timing controller initializes communication with a plurality of source drivers by transmitting link data through a plurality of data channels and monitors source driver status through an auxiliary status channel. The plurality of source drivers share the auxiliary status channel to indicate their status. The timing controller transmits display data to a source driver through a data channel. The display data includes a request for status data from the source driver. The source driver transmits the requested status data to the timing controller via the auxiliary status channel.

    摘要翻译： 公开了用于面板内通信接口的系统和方法，其特征在于提高了系统可靠性并减少了总线宽度。 定时控制器通过多个数据信道发送链路数据并通过辅助状态信道监视源驱动器状态来初始化与多个源驱动器的通信。 多个源驱动器共享辅助状态通道以指示其状态。 定时控制器通过数据通道将显示数据发送到源驱动器。 显示数据包括来自源驱动器的状态数据请求。 源驱动器通过辅助状态通道将所请求的状态数据发送到定时控制器。

    Compounds which have activity at M1 receptor and their uses in medicine
    9.
    发明授权
    Compounds which have activity at M1 receptor and their uses in medicine 失效
    具有M1受体活性的化合物及其在药物中的用途

    公开(公告)号：US08481566B2

    公开(公告)日：2013-07-09

    申请号：US11852455

    申请日：2007-09-10

    申请人： Brian Budzik ,  David Gwyn Cooper ,  Ian Thomson Forbes ,  Vincenzo Garzya ,  Jian Jin ,  Dongchuan Shi ,  Graham Walker

    发明人： Brian Budzik ,  David Gwyn Cooper ,  Ian Thomson Forbes ,  Vincenzo Garzya ,  Jian Jin ,  Dongchuan Shi ,  Graham Walker

    IPC分类号： A61K31/445 ,  C07D401/04

    CPC分类号： C07D405/12 ,  C07D235/26

    摘要： Compounds of formula (I) and salts and solvates are provided: wherein R4 is fluoro, R5 is selected from hydrogen, halogen, cyano, C1-6alkyl, C1-6alkyl substituted with one or more fluorine atoms, C1-6alkoxy, and C1-6alkoxy substituted with one or more fluorine atoms; and R6 is selected from halogen, cyano, C1-6alkyl, C1-6alkyl substituted with one or more fluorine atoms, C3-6cycloalkyl, C3-6cycloalkyl substituted with one or more fluorine atoms, C1-6alkoxy and C1-6alkoxy substituted with one or more fluorine atoms, and Q is hydrogen or C1-6alkyl. The compounds are expected to be useful for therapy, for example in the treatment of psychotic disorders and cognitive impairment.

    摘要翻译： 提供式（I）化合物和盐和溶剂合物：其中R4是氟，R5选自氢，卤素，氰基，C1-6烷基，被一个或多个氟原子取代的C1-6烷基，C1-6烷氧基和C1- 6个被一个或多个氟原子取代的烷氧基; 并且R 6选自卤素，氰基，C 1-6烷基，被一个或多个氟原子取代的C 1-6烷基，C 3-6环烷基，被一个或多个氟原子取代的C 3-6环烷基，C 1-6烷氧基和被一个或多个氟原子取代的C 1-6烷氧基 更多的氟原子，Q是氢或C 1-6烷基。 预期化合物可用于治疗，例如治疗精神病和认知障碍。