Invention Grant
- Patent Title: Process for making mycophenolate mofetil by transesterification
- Patent Title (中): 通过酯交换制备霉酚酸酯的方法
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Application No.: US10750466Application Date: 2003-12-29
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Publication No.: US07019133B2Publication Date: 2006-03-28
- Inventor: Kwang-Chung Lee , Shu-Chuan Lin , Ray-Hwa Chiu
- Applicant: Kwang-Chung Lee , Shu-Chuan Lin , Ray-Hwa Chiu
- Applicant Address: TW Taipei Hsien
- Assignee: Chunghwa Chemical Synthesis & Biotech Co., Ltd.
- Current Assignee: Chunghwa Chemical Synthesis & Biotech Co., Ltd.
- Current Assignee Address: TW Taipei Hsien
- Priority: TW92103728 20030221
- Main IPC: C07D413/02
- IPC: C07D413/02
Abstract:
A process for making mycophenolate mofetil comprising: conducting a catalytic transesterification by reacting a low-carbon alkyl ester of mycophenolic acid with 2-morpholinoethanol [also named as 4-(2-hydroxyethyl) morpholine] to obtain a crude product of mycophenolate mofetil, which is then isolated and purified.
Public/Granted literature
- US20040167130A1 Process for making mycophenolate mofetil by transesterification Public/Granted day:2004-08-26
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