Invention Grant
- Patent Title: Process for synthesizing beta-lactam
- Patent Title (中): β-内酰胺合成方法
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Application No.: US10450450Application Date: 2001-03-07
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Publication No.: US07022842B2Publication Date: 2006-04-04
- Inventor: Kiyotaka Hatakeda , Osamu Sato , Mitsuhiro Kanakubo , Yutaka Ikushima , Kazuo Torii
- Applicant: Kiyotaka Hatakeda , Osamu Sato , Mitsuhiro Kanakubo , Yutaka Ikushima , Kazuo Torii
- Applicant Address: JP Tokyo
- Assignee: National Institute of Advanced Industrial Science and Technology
- Current Assignee: National Institute of Advanced Industrial Science and Technology
- Current Assignee Address: JP Tokyo
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, P.C.
- Priority: JP2000-389408 20001221
- International Application: PCT/JP01/01759 WO 20010307
- International Announcement: WO02/50025 WO 20020627
- Main IPC: C07B43/06
- IPC: C07B43/06 ; C07D205/08
Abstract:
It is an object of the present invention to provide a method for synthesizing β-lactams and a method for manufacturing β-lactams in water of high-temperature and under high-pressure, and the present invention relates to a β-lactam synthesis method which is characterized in that β-lactams are synthesized by reacting β-amino acids in water at high-temperature and under high-pressure, this method being further characterized in that β-lactams are synthesized at a high speed by cyclizing β-amino acids in water at high-temperature and under high-pressure in which the temperature range is 200° C. or higher and the pressure range is 10 MPa or greater, and the present invention also relates to a method for manufacturing β-lactams which is characterized in that β-lactams are synthesized by reacting β-amino acids in water at high-temperature and under high-pressure, and are then separated and purified using a column separation medium.
Public/Granted literature
- US20040030126A1 Process for synthesizing beta-lactam Public/Granted day:2004-02-12
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