- 专利标题： Atropisomers of asymmetric xanthene fluorescent dyes and methods of DNA sequencing and fragment analysis
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申请号： US10716165申请日： 2003-11-18
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公开(公告)号： US07038063B2公开(公告)日： 2006-05-02
- 发明人: Linda G. Lee , Meng C. Taing , Barnett B. Rosenblum
- 申请人： Linda G. Lee , Meng C. Taing , Barnett B. Rosenblum
- 申请人地址： US CA Foster City
- 专利权人： Applera Corporation
- 当前专利权人： Applera Corporation
- 当前专利权人地址： US CA Foster City
- 代理商 Alex Andrus; Vincent M Powers
- 主分类号： C07D311/82
- IPC分类号： C07D311/82
摘要：
Atropisomeric energy-transfer dye compounds are disclosed. A variety of molecular biology applications utilize atropisomeric xanthene fluorescent dyes as labels for substrates such as nucleotides, nucleosides, polynucleotides, polypeptides and carbohydrates. Methods include DNA sequencing, DNA fragment analysis, PCR, SNP analysis, oligonucleotide ligation, amplification, minisequencing, and primer extension.
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