发明授权
- 专利标题： Purified and isolated platelet calcium channel nucleic acids
- 专利标题（中）： 纯化和分离的血小板钙通道核酸
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申请号： US10029413申请日： 2001-12-20
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公开(公告)号： US07041475B2公开(公告)日： 2006-05-09
- 发明人: Nadia Malouf , Timothy C. Nichols
- 申请人： Nadia Malouf , Timothy C. Nichols
- 申请人地址： US NC Chapel Hill
- 专利权人： University of North Carolina at Chapel Hill
- 当前专利权人： University of North Carolina at Chapel Hill
- 当前专利权人地址： US NC Chapel Hill
- 代理机构： Jenkins, Wilson & Taylor, P-A-
- 主分类号： C12N15/00
- IPC分类号： C12N15/00 ; C12N15/12 ; C12N15/63 ; C07K14/00 ; C07H21/04
摘要：
Isolated and purified platelet voltage dependent calcium channel (VDCC) α1 subunit polypeptides, and nucleic acid molecules encoding the same. Recombinant host cells, recombinant nucleic acids and recombinant proteins are also disclosed, along with methods of producing each. Isolated and purified antibodies to platelet VDCC α1 subunit polypeptides, and methods of producing the same, are also disclosed. Platelet VDCC α1 subunit polypeptides have biological activity in calcium transport. Thus, therapeutic and diagnostic methods involving this activity are also disclosed.
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