发明授权
- 专利标题: Therapeutic benzoxazole compounds
- 专利标题(中): 治疗性苯并恶唑化合物
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申请号: US10450927申请日: 2001-12-19
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公开(公告)号: US07045539B2公开(公告)日: 2006-05-16
- 发明人: Bernard Barlaam , Peter Bernstein , Cathy Dantzman , Paul Warwick
- 申请人: Bernard Barlaam , Peter Bernstein , Cathy Dantzman , Paul Warwick
- 申请人地址: SE Sodertalje
- 专利权人: AstraZeneca AB
- 当前专利权人: AstraZeneca AB
- 当前专利权人地址: SE Sodertalje
- 代理机构: White & Case LLP
- 优先权: SE0004825 20001222; SE0004826 20001222
- 国际申请: PCT/SE01/02855 WO 20011219
- 国际公布: WO02/051821 WO 20020704
- 主分类号: A61K31/425
- IPC分类号: A61K31/425 ; C07D277/62 ; A61P25/00
摘要:
Compounds of the formula (I) for use as an estrogen receptor-β-selective ligand are described wherein: X is O or S; and R1, R3 R6 are as described in the specification. The use of these compounds in treating Alzheimer's disease, anxiety disorders, depressive disorders, osteoporosis, cardiovascular disease, rheumatoid arthritis and prostate cancer is described; as are processes for making them.
公开/授权文献
- US20040102435A1 Therapeutic compounds 公开/授权日:2004-05-27
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