发明授权
- 专利标题： Bifunctional chelating agent for actinium
- 专利标题（中）： 双功能锕系螯合剂
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申请号： US10488938申请日： 2002-09-13
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公开(公告)号： US07045606B2公开(公告)日： 2006-05-16
- 发明人: Ali Ouadi , Jean-Francois Gestin , Christos Apostolidis
- 申请人： Ali Ouadi , Jean-Francois Gestin , Christos Apostolidis
- 申请人地址： BE Brussels
- 专利权人： European Community
- 当前专利权人： European Community
- 当前专利权人地址： BE Brussels
- 代理机构： Oblon, Spivak, McClelland, Maier & Neustadt, P.C.
- 优先权： LU90834 20010917
- 国际申请： PCT/EP02/10306 WO 20020913
- 国际公布： WO03/024940 WO 20030327
- 主分类号： C07K16/00
- IPC分类号： C07K16/00 ; C07D259/00 ; G01N33/534 ; C12N9/96 ; A61K51/00
摘要：
The invention concerns a ligand comprising (I) wherein n is an integer from 1 to 5 Y is CO2H or PO3H2T represents —X or -phenyl-X, wherein X represents NO2, NH2, NCS, NHCOCH2-Z, NHCO—W—COCNHS, —NH-Q, —NHCS-Q, —NHCOCH2-Q, or NHCO(CH2)m-Q where Q is a hapten chosen from the group consisting of steroids, enzymes, proteins, monoclonal antibodies, chimeric antibodies, or fragments thereof or any activated linker ready for coupling reaction, W is —(CH2)m- m is an integer from 1 to 10 Z is chloride, bromide or iodine
公开/授权文献
- US20040242852A1 Bifunctional chelating agent for actinium 公开/授权日：2004-12-02
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