Invention Grant
- Patent Title: High efficiency retroviral vector which contains genetically engineered cellular non-coding sequence harboring splicing acceptor
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Application No.: US10129422Application Date: 2001-09-08
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Publication No.: US07049143B2Publication Date: 2006-05-23
- Inventor: Sun-Young Kim , Seung-Shin Yu , Jun-Tae Lee
- Applicant: Sun-Young Kim , Seung-Shin Yu , Jun-Tae Lee
- Applicant Address: KR
- Assignee: ViroMed Co., Ltd.
- Current Assignee: ViroMed Co., Ltd.
- Current Assignee Address: KR
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Priority: KR10-2000-0053613 20000908
- International Application: PCT/KR01/01515 WO 20010908
- International Announcement: WO02/20810 WO 20020314
- Main IPC: C12N5/10
- IPC: C12N5/10 ; C12N1/21 ; C12N15/867 ; C12N15/63

Abstract:
The present invention provides a safe and highly efficient retroviral vector derived from the MLV (murine leukemia virus) for use in gene therapy, which lacks viral coding sequences but contains the genetically engineered EF Iα non-coding sequence harboring splicing acceptor.
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