Invention Grant
- Patent Title: Processes for purifying and for detecting target double-stranded DNA sequences by triple helix interaction
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Application No.: US10104025Application Date: 2002-03-25
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Publication No.: US07052838B2Publication Date: 2006-05-30
- Inventor: Francis Blanche , Béatrice Cameron
- Applicant: Francis Blanche , Béatrice Cameron
- Applicant Address: FR Vitry sur Séine
- Assignee: Centelion
- Current Assignee: Centelion
- Current Assignee Address: FR Vitry sur Séine
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner LLP
- Priority: FR0103953 20010323
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34 ; C07H21/02

Abstract:
The present invention relates to novel target double-stranded DNA sequences capable of interacting with a third strand and of forming a stable triple helix. The present invention also relates to a process for purifying a double-stranded DNA molecule, according to which a solution containing said DNA molecule is brought into contact with a third DNA strand capable of forming, by hybridization, a triple helix structure with a target double-stranded DNA sequence carried by said DNA molecule.
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