发明授权
US07053077B1 Use of biogenic estrogen sulfamates for hormone replacement therapy
有权
使用生物源性雌激素氨基磺酸盐治疗激素替代疗法
- 专利标题： Use of biogenic estrogen sulfamates for hormone replacement therapy
- 专利标题（中）： 使用生物源性雌激素氨基磺酸盐治疗激素替代疗法
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申请号： US09744574申请日： 1999-05-13
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公开(公告)号： US07053077B1公开(公告)日： 2006-05-30
- 发明人: Walter Elger , Pekka Lähteenmäki , Matti Lehtinen , Gudrun Reddersen , Holger Zimmermann , Michael Oettel , Sigfrid Schwarz
- 申请人： Walter Elger , Pekka Lähteenmäki , Matti Lehtinen , Gudrun Reddersen , Holger Zimmermann , Michael Oettel , Sigfrid Schwarz
- 申请人地址： DE Berlin
- 专利权人： Schering AG
- 当前专利权人： Schering AG
- 当前专利权人地址： DE Berlin
- 代理机构： Millen, White, Zelano & Branigan, P.C.
- 优先权： DE19834931 19980728
- 国际申请： PCT/DE99/01496 WO 19990513
- 国际公布： WO00/06175 WO 20000210
- 主分类号： A61K31/56
- IPC分类号： A61K31/56
摘要：
The invention relates to the use of biogenic estrogen sulfamates for the oral discontinuous application for hormone replacement therapy (HRT). The discontinuous administration takes place in intervals ranging from 2 to 40 days. The invention also provides the additional application of gestagens, preferably continuously in the form of an implant or in the form of an intrauterine releasing system (IUD). Estrone sulfamate, estradiol sulfamate or an N-acyl sulfamate of estrone, estradiol or estriol having up to 7 C-atoms in the acyl chain, or a combination comprised of two or more of said active ingredients are used as biogenic estrogen sulfamates.