Invention Grant
US07067302B2 DNA and amino acid sequence of a tyrosine ammonia lyase enzyme from the bacterium Rhodobacter sphaeroides
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来自细菌Rhodobacter sphaeroides的酪氨酸氨裂解酶的DNA和氨基酸序列
- Patent Title: DNA and amino acid sequence of a tyrosine ammonia lyase enzyme from the bacterium Rhodobacter sphaeroides
- Patent Title (中): 来自细菌Rhodobacter sphaeroides的酪氨酸氨裂解酶的DNA和氨基酸序列
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Application No.: US10621826Application Date: 2003-07-17
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Publication No.: US07067302B2Publication Date: 2006-06-27
- Inventor: Lixuan Huang , Zhixiong Xue
- Applicant: Lixuan Huang , Zhixiong Xue
- Applicant Address: US DE Wilmington
- Assignee: E. I. du Pont de Nemours and Company
- Current Assignee: E. I. du Pont de Nemours and Company
- Current Assignee Address: US DE Wilmington
- Main IPC: C12N15/63
- IPC: C12N15/63 ; C12N9/88 ; C07H21/04
Abstract:
A novel tyrosine ammonia lyase enzyme was identified in the bacterium Rhodobacter sphaeroides. This enzyme has a higher activity for tyrosine than for phenylalanine and is useful for the production of para-hydroxycinnamic acid directly from tyrosine. The gene encoding this enzyme was cloned by direct amplification using the genomic DNA and was expressed in E. coli.
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