发明授权
- 专利标题： Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor
- 专利标题（中）： 黑色素浓缩激素对黑色素浓缩激素受体的拮抗作用
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申请号： US11022453申请日： 2004-12-22
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公开(公告)号： US07071182B2公开(公告)日： 2006-07-04
- 发明人: Andrew J. Souers , Christine A. Collins , Ju Gao , Andrew S. Judd , Philip R. Kym , Mathew M. Mulhern , Hing L. Sham , Dariusz Wodka
- 申请人： Andrew J. Souers , Christine A. Collins , Ju Gao , Andrew S. Judd , Philip R. Kym , Mathew M. Mulhern , Hing L. Sham , Dariusz Wodka
- 申请人地址： US IL Abbott Park
- 专利权人： Abbott Laboratories
- 当前专利权人： Abbott Laboratories
- 当前专利权人地址： US IL Abbott Park
- 代理商 Johanna M. Corbin
- 主分类号： A61K31/55
- IPC分类号： A61K31/55 ; A61K31/5377 ; A61K31/454 ; A61K31/416 ; A61K31/4439
摘要：
The present invention relates to the antagonism of the effects of melanin-concentrating hormone (MCH) through the melanin concentrating hormone receptor which is useful for the prevention or treatment of eating disorders, weight gain, obesity, abnormalities in reproduction and sexual behavior, thyroid hormone secretion, diuresis and water/electrolyte homeostasis, sensory processing, memory, sleeping, arousal, anxiety, depression, seizures, neurodegeneration and psychiatric disorders.
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