发明授权
- 专利标题: Resorbable interbody spinal fusion devices
- 专利标题(中): 可再生体内脊柱融合装置
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申请号: US09785593申请日: 2001-02-16
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公开(公告)号: US07077866B2公开(公告)日: 2006-07-18
- 发明人: Joseph D. Gresser , Debra J. Trantolo , Robert S. Langer , Kai-Uwe Lewandrowski , Alexander M. Klibanov , Donald L. Wise
- 申请人: Joseph D. Gresser , Debra J. Trantolo , Robert S. Langer , Kai-Uwe Lewandrowski , Alexander M. Klibanov , Donald L. Wise
- 申请人地址: US MA Norwood
- 专利权人: DePuy Mitek, Inc.
- 当前专利权人: DePuy Mitek, Inc.
- 当前专利权人地址: US MA Norwood
- 代理机构: Pabst Patent Group LLP
- 主分类号: A61F2/44
- IPC分类号: A61F2/44
摘要:
A resorbable interbody fusion device for use in spinal fixation is disclosed. The device is composed of 25–100% bioresorbable or resorbable material. The interbody fusion device of the invention can be in any convenient form, such as a wedge, screw or cage. Preferably, the resorbable device of the invention is in the shape of a tapered wedge or cone, which further desirably incorporates structural features such as serrations or threads better to anchor the device in the adjoining vertebrae. The preferred device further comprises a plurality of peripheral voids and more desirably a central void space therein, which may desirably be filled with a grafting material for facilitating bony development and/or spinal fusion, such as an autologous grafting material. As the preferred material from which the resorbable interbody fusion device is manufactured is most likely to be a polymer that can produce acidic products upon hydrolytic degradation, the device preferably further includes a neutralization compound, or buffer, in sufficiently high concentration to decrease the rate of pH change as the device degrades, in order to prevent sterile abscess formation caused by the accumulation of unbuffered acidic products in the area of the implant.
公开/授权文献
- US20010008980A1 Resorbable interbody spinal fusion devices 公开/授权日:2001-07-19
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