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US07081260B2 α-Glucosidase inhibitors from a natural source 失效
来自天然来源的α-葡萄糖苷酶抑制剂

α-Glucosidase inhibitors from a natural source
Abstract:
The present invention relates to a method for providing α-glucosidase inhibition to a subject by administering a pharmaceutical composition comprising a α-glucosidase inhibitory agent selected from pipataline (formula 1a), sesamin (formula 1b), pellitorine (Formula 1c), guineensine (Formula 1d) and brachystamide-B (formula 1e) having therapeutic application for diabetes mellitus, cancer, viral diseases such as hepatitis B and C, HIV, AIDS etc; also the invention provides a process for the isolation of said α-glucosidase inhibitory agent from the plant source Piper longum in significant yields.
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