发明授权
US07087394B2 Methods and compositions for treating and diagnosing diabetes and related diseases involving beta-TRP
失效
用于治疗和诊断涉及β-TRP的糖尿病和相关疾病的方法和组合物
- 专利标题: Methods and compositions for treating and diagnosing diabetes and related diseases involving beta-TRP
- 专利标题(中): 用于治疗和诊断涉及β-TRP的糖尿病和相关疾病的方法和组合物
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申请号: US10794897申请日: 2004-03-04
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公开(公告)号: US07087394B2公开(公告)日: 2006-08-08
- 发明人: Jeffrey D. Johnson , Yun-Ping Zhou
- 申请人: Jeffrey D. Johnson , Yun-Ping Zhou
- 申请人地址: US CA Hayward
- 专利权人: Metabolex, Inc.
- 当前专利权人: Metabolex, Inc.
- 当前专利权人地址: US CA Hayward
- 代理机构: Townsend and Townsend and Crew LLP
- 主分类号: G01N33/53
- IPC分类号: G01N33/53 ; C12N15/63 ; A01N38/00
摘要:
Expression of beta-TRP is enriched in islet cells. Introduction of expression cassettes encoding beta-TRP into diabetic islet cells improved glucose-stimulated insulin production. Therefore, the invention provides methods of identifying beta-TRP modulators for treating diabetic individuals and introducing beta-TRP into islet cells
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