发明授权
- 专利标题: Process for producing chromone compound
- 专利标题(中): 色酮化合物的制备方法
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申请号: US10506119申请日: 2003-02-27
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公开(公告)号: US07094914B2公开(公告)日: 2006-08-22
- 发明人: Hiroaki Hibino , Susumu Ohtsuka , Yasunobu Miyamoto , Tomoyasu Yoshida , Itsuo Okumoto
- 申请人: Hiroaki Hibino , Susumu Ohtsuka , Yasunobu Miyamoto , Tomoyasu Yoshida , Itsuo Okumoto
- 申请人地址: JP Osaka JP Osaka
- 专利权人: Sumitomo Chemical Company, Limited,Ono Pharmaceutical Co., Ltd.
- 当前专利权人: Sumitomo Chemical Company, Limited,Ono Pharmaceutical Co., Ltd.
- 当前专利权人地址: JP Osaka JP Osaka
- 代理机构: Wenderoth, Lind & Ponack, L.L.P.
- 优先权: JP2002-053315 20020228; JP2002-053316 20020228; JP2002-169675 20020611; JP2002-169676 20020611
- 国际申请: PCT/JP03/02182 WO 20030227
- 国际公布: WO03/080555 WO 20031002
- 主分类号: C07D311/24
- IPC分类号: C07D311/24 ; C07C205/37
摘要:
A process for producing a dicarboxylic acid compound represented by the formula (4): wherein R1 and R2 are the same or different and each represents lower alkyl and the wavy line indicates that this compound is the E- or Z-isomer or a mixture of them, characterized by reacting a compound represented by the formula (2): wherein R1, R2 and the wavy line have the same meanings as the above, and one of X2 and X3 represents hydrogen and the other represents halogen, with nitrophenol represented by the formula (3): in the presence of a base; a process for producing a nitrochromone compound represented by the formula (5): wherein R1 has the same meaning as the above, characterized by reacting the dicarboxylic acid compound or carboxylic acid thereof with an acid; a process for producing an aminochromone compound which comprises reducing the nitrochromone compound; and a process for producing an amidochromone compound which comprises acylating the aminochromone compound are provided.
公开/授权文献
- US20050085664A1 Process for producing chromone compound 公开/授权日:2005-04-21
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