发明授权
- 专利标题： Depsipeptide compound
- 专利标题（中）： 去磷脂化合物
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申请号： US10525717申请日： 2003-08-28
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公开(公告)号： US07098186B2公开(公告)日： 2006-08-29
- 发明人: Koji Nagai , Masatoshi Taniguchi , Nobuaki Shindo , Yoh Terada , Masamichi Mori , Nobuaki Amino , Ken-ichi Suzumura , Isao Takahashi , Mitsuo Amase
- 申请人： Koji Nagai , Masatoshi Taniguchi , Nobuaki Shindo , Yoh Terada , Masamichi Mori , Nobuaki Amino , Ken-ichi Suzumura , Isao Takahashi , Mitsuo Amase
- 申请人地址： JP Tokyo
- 专利权人： Astellas Pharma INC
- 当前专利权人： Astellas Pharma INC
- 当前专利权人地址： JP Tokyo
- 代理机构： Sughrue Mion, PLLC
- 优先权： JP2002-255141 20020830
- 国际申请： PCT/JP03/10957 WO 20030828
- 国际公布： WO2004/020460 WO 20041103
- 主分类号： A61K38/12
- IPC分类号： A61K38/12 ; C07K2/00
摘要：
The present invention relates to a novel compound which is useful as an agent for prevention and treatment of diseases associated with HDAC, in particular, tumor or cell proliferative diseases. The depsipeptide compound or its pharmaceutically acceptable salt of the present invention has a good HDAC inhibitory activity and an inhibitory activity of cell proliferation against human cancer cells and, therefore, is useful in treatment and improvement of diseases and pathogenic conditions associated with histone acetylation, in particular, tumor or cell proliferative diseases.
公开/授权文献
- US20050209134A1 Novel depsipeptide compound 公开/授权日：2005-09-22
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