发明授权
US07098243B2 Bicyclic carbohydrates as antiviral bioactives for the treatment of infections caused by the alphaherpesvirinae HSV-1 and HSV-2
失效
双环碳水化合物作为抗病毒生物活性物质，用于治疗由αherpesvirinaeHSV-1和HSV-2引起的感染
- 专利标题： Bicyclic carbohydrates as antiviral bioactives for the treatment of infections caused by the alphaherpesvirinae HSV-1 and HSV-2
- 专利标题（中）： 双环碳水化合物作为抗病毒生物活性物质，用于治疗由αherpesvirinaeHSV-1和HSV-2引起的感染
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申请号： US10663962申请日： 2003-09-16
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公开(公告)号： US07098243B2公开(公告)日： 2006-08-29
- 发明人: Benedikt Sas , Johan Van hemel , Jan Vandenkerckhove , Eric Peys , Johan Van Der Eycken , Steven Van Hoof
- 申请人： Benedikt Sas , Johan Van hemel , Jan Vandenkerckhove , Eric Peys , Johan Van Der Eycken , Steven Van Hoof
- 申请人地址： US IA Des Moines
- 专利权人： Kemin Pharma Europe B.V.B.A.
- 当前专利权人： Kemin Pharma Europe B.V.B.A.
- 当前专利权人地址： US IA Des Moines
- 代理商 Kent A. Herink; Daniel A. Rosenberg; Emily E. Harris
- 主分类号： A61K31/70
- IPC分类号： A61K31/70 ; C07D493/02
摘要：
Novel bicyclic carbohydrate compounds are effective for the prophylaxis and treatment of diseases caused by infections of the alphaherpesvirinae HSV-1 and HSV-2. The invention includes the compound wherein X1, X2, and X3 are selected from the group consisting of O, N, and S; wherein Y1 and Y2 are selected from the group consisting of O, N, and S; and wherein Z is selected from the group consisting of F, Cl, and Br, as well as analogs, prodrugs and pharmaceutically acceptable salts thereof, together with pharmaceutical compositions for the prophylaxis and treatment of diseases caused by infections of alphaherpesvirinae.
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