发明授权
![5,8-Dihydro-6H-pyrido[2,3-d]pyrimidin-7-ones](/docs/US/2006-08-29/US07098332B2/abs.jpg.600x600.jpg)
- 专利标题： 5,8-Dihydro-6H-pyrido[2,3-d]pyrimidin-7-ones
- 专利标题（中）： 5,8-二氢-6H-吡啶并[2,3-d]嘧啶-7-酮
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申请号： US10731594申请日： 2003-12-08
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公开(公告)号： US07098332B2公开(公告)日： 2006-08-29
- 发明人: Jin-Jun Liu , Kin-Chun Luk
- 申请人： Jin-Jun Liu , Kin-Chun Luk
- 申请人地址： US NJ Nutley
- 专利权人： Hoffmann-La Roche Inc.
- 当前专利权人： Hoffmann-La Roche Inc.
- 当前专利权人地址： US NJ Nutley
- 代理商 George W. Johnston; Patricia S. Rocha-Tramaloni; David E. Wildman
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; A61K31/519
![5,8-Dihydro-6H-pyrido[2,3-d]pyrimidin-7-ones](/abs-image/US/2006/08/29/US07098332B2/abs.jpg.150x150.jpg)
摘要：
The invention provides 5,8-dihydro-6H-pyrido[2,3-d]pyrimidin-7-one compounds that are selective inhibitors of KDR and FGFR kinases, and are useful in the treatment of cancers. The compounds have the generic structure I where Ar, Ar′, and R1 are as set forth in the present specification. The invention also provides pharmaceutical compositions containing these compounds and methods for their use.
公开/授权文献
- US20040122029A1 Novel dihydropyridinone compounds 公开/授权日：2004-06-24