发明授权
US07105580B2 Porous structures useful for growing living tissue, and methods of manufacture
失效
用于生长生物体组织的多孔结构及其制造方法
- 专利标题： Porous structures useful for growing living tissue, and methods of manufacture
- 专利标题（中）： 用于生长生物体组织的多孔结构及其制造方法
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申请号： US10314453申请日： 2002-12-05
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公开(公告)号： US07105580B2公开(公告)日： 2006-09-12
- 发明人: Prabha D. Nair , Buddy D. Ratner , Viola Vogel , Robert M. Nerem
- 申请人： Prabha D. Nair , Buddy D. Ratner , Viola Vogel , Robert M. Nerem
- 申请人地址： US WA Seattle
- 专利权人： University of Washington
- 当前专利权人： University of Washington
- 当前专利权人地址： US WA Seattle
- 代理机构： Christensen O'Connor Johnson Kindness PLLC
- 主分类号： B01J13/00
- IPC分类号： B01J13/00 ; C12N5/00 ; C12N5/02
摘要：
In one aspect the present invention provides biodegradable, porous structures that each include a structural framework, wherein the structural framework includes: (a) a solidified mixture of polymer molecules and amino acid molecules, wherein at least some of the amino acid molecules are linked to other amino acid molecules within the framework; and (b) a multiplicity of interconnected spaces defined by the structural framework. In some embodiments, the porous structures of the invention are adapted to physically support the growth of living cells in vitro or in vivo, and can be used to grow living tissue and/or living organs. The present invention also provide methods for making the biodegradable, porous structures of the invention.
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