Invention Grant
- Patent Title: Methods of identifying modulators of the FGF receptor
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Application No.: US09757415Application Date: 2001-01-09
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Publication No.: US07108984B2Publication Date: 2006-09-19
- Inventor: Ming-Ming Zhou , Mitchell Goldfarb
- Applicant: Ming-Ming Zhou , Mitchell Goldfarb
- Applicant Address: US NY New York
- Assignee: Mount Sinai School of Medicine
- Current Assignee: Mount Sinai School of Medicine
- Current Assignee Address: US NY New York
- Agency: Klauber & Jackson
- Main IPC: G01N33/53
- IPC: G01N33/53
Abstract:
The present invention provides fragments of SNT and FGFR which can form a binding complex that is amenable to structural determinations by NMR spectroscopy. The three-dimensional structural data is also included as part of the invention. In addition, the present invention provides methodology for related structure based rational drug design using the three-dimensional data. Nucleotide and amino acid sequences of the fragments are also provided.
Public/Granted literature
- US20030040612A1 Methods of identifying modulators of the FGF receptor Public/Granted day:2003-02-27
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