- 专利标题： Display of receptors and analysis of binding interactions and drug libraries
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申请号： US10101870申请日： 2002-03-21
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公开(公告)号： US07109041B1公开(公告)日： 2006-09-19
- 发明人: Larry Sklar , Eric Prossnitz , Vilven Janeen , Donna Neldon
- 申请人： Larry Sklar , Eric Prossnitz , Vilven Janeen , Donna Neldon
- 申请人地址： US NM Albuquerque
- 专利权人： Science & Technology Corporation @University of New Mexico
- 当前专利权人： Science & Technology Corporation @University of New Mexico
- 当前专利权人地址： US NM Albuquerque
- 代理商 Henry D. Coleman; R. Neil Sudol; William J. Sapone
- 主分类号： G01N33/566
- IPC分类号： G01N33/566 ; C07K1/00 ; C12P21/02 ; C12N1/20 ; C07H21/04
摘要：
A display and method of preparing 7-transmembrane and other receptors for real-time kinetic analysis of binding interactions. The invention includes display on beads and in micelles for multi-well and flow cytometric analysis. The invention is useful for ligand discovery and drug action discovery, and G-protein response in particular.