发明授权
- 专利标题: Minimally compliant, volume-efficient piston for osmotic drug delivery systems
- 专利标题(中): 适用于渗透药物输送系统的容积效率活塞
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申请号: US11219960申请日: 2005-09-06
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公开(公告)号: US07112335B2公开(公告)日: 2006-09-26
- 发明人: Scott D. Lautenbach
- 申请人: Scott D. Lautenbach
- 申请人地址: US CA Mountain View
- 专利权人: Alza Corporation
- 当前专利权人: Alza Corporation
- 当前专利权人地址: US CA Mountain View
- 代理机构: TraskBritt
- 主分类号: A61F2/00
- IPC分类号: A61F2/00 ; A61K9/22
摘要:
An osmotic pump having a minimally compliant, volume-efficient piston positioned within a capsule is provided. The capsule has an interior surface, a beneficial agent, and an osmotic agent. The piston is movable with respect to an interior surface of the capsule, and defines a movable seal with the interior surface of the capsule. The movable seal separates the osmotic agent from the beneficial agent. The piston has a length-to-total-diameter ratio of about 1.1:1 and a core-diameter-to-total-diameter ratio of about 0.9:1. The piston enables greater beneficial agent and/or osmotic agent payload without increasing the size of the capsule. The osmotic agent imbibes liquid from a surrounding environment through a semipermeable body to cause the piston to move and, in turn, cause delivery of the beneficial agent from the capsule.
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