发明授权
- 专利标题： Bicyclic 6-alkylidene-penems as β-lactamase inhibitors
- 专利标题（中）： 双环6-亚烷基 - 青霉烯作为β-内酰胺酶抑制剂
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申请号： US10427380申请日： 2003-05-01
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公开(公告)号： US07112582B2公开(公告)日： 2006-09-26
- 发明人: Aranapakam Mudumbai Venkatesan , Tarek Suhayl Mansour , Takao Abe , Itsuki Yamamura , Tsuyoshi Takasaki , Atul Agarwal , Osvaldo dos Santos , Fuk-Wah Sum , Yang-I Lin
- 申请人： Aranapakam Mudumbai Venkatesan , Tarek Suhayl Mansour , Takao Abe , Itsuki Yamamura , Tsuyoshi Takasaki , Atul Agarwal , Osvaldo dos Santos , Fuk-Wah Sum , Yang-I Lin
- 申请人地址： US NJ Madison
- 专利权人： Wyeth
- 当前专利权人： Wyeth
- 当前专利权人地址： US NJ Madison
- 代理机构： Wilmer Cutler Pickering Hale and Dorr LLP
- 主分类号： C07D499/881
- IPC分类号： C07D499/881 ; C07D519/06 ; C07D513/04 ; A61K31/431 ; A61P31/04
摘要：
The present invention provides a compound of formula I, pharmaceutical compositions and the use thereof for the treatment of bacterial infection or disease in a patient in need thereof. wherein one of A and B denotes hydrogen and the other an optionally substituted fused bicyclic heteroaryl group; and X is S.
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