发明授权
US07118869B2 Genomic sequence of the 5-Lipoxygenase-activating protein (FLAP), polymorphic markers thereof and methods for detection of asthma
失效
5-脂氧合酶活化蛋白（FLAP）的基因组序列及其多态性标记及哮喘检测方法
- 专利标题： Genomic sequence of the 5-Lipoxygenase-activating protein (FLAP), polymorphic markers thereof and methods for detection of asthma
- 专利标题（中）： 5-脂氧合酶活化蛋白（FLAP）的基因组序列及其多态性标记及哮喘检测方法
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申请号： US10359512申请日： 2003-02-05
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公开(公告)号： US07118869B2公开(公告)日： 2006-10-10
- 发明人: Marta Blumenfeld , Ilya Chumakov , Lydie Bougueleret
- 申请人： Marta Blumenfeld , Ilya Chumakov , Lydie Bougueleret
- 申请人地址： FR Evry
- 专利权人： Serono Genetics Institute S.A.
- 当前专利权人： Serono Genetics Institute S.A.
- 当前专利权人地址： FR Evry
- 代理机构： Saliwanchik, Lloyd & Saliwanchik
- 主分类号： C07H21/04
- IPC分类号： C07H21/04 ; C12Q1/68
摘要：
The invention concerns the genomic sequence of the FLAP gene. The invention also concerns biallelic markers of a FLAP gene and the association established between these markers and diseases involving the leukotriene pathway such as asthma. The invention provides means to determine the predisposition of individuals to diseases involving the leukotriene pathway as well as means for the diagnosis of such diseases and for the prognosis/detection of an eventual treatment response to agents acting on the leukotriene pathway.
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