- 专利标题: Modified carrier particles for use in dry powder inhalers
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申请号: US10628453申请日: 2003-07-29
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公开(公告)号: US07132115B2公开(公告)日: 2006-11-07
- 发明人: Rossella Musa , Roberto Bilzi , Paolo Ventura , Paolo Chiesi
- 申请人: Rossella Musa , Roberto Bilzi , Paolo Ventura , Paolo Chiesi
- 申请人地址: IT Parma
- 专利权人: Chiesi Farmaceutici S.p.A.
- 当前专利权人: Chiesi Farmaceutici S.p.A.
- 当前专利权人地址: IT Parma
- 代理机构: Oblon, Spivak, McClelland, Maier & Neustadt, P.C.
- 优先权: ITMI99A0455 19990305
- 主分类号: A61K9/14
- IPC分类号: A61K9/14 ; A61K9/00 ; A61K9/72
摘要:
The invention relates to carrier particles for use in pharmaceutical compositions for the pulmonary administration of medicaments by means of dry powder inhalers. In particular, the invention relates to a novel technological process for obtaining a carrier modified so as to improve the efficiency of redispersion of active particles and hence increase the respirable fraction. After the treatment of the invention, the surface of said modified carrier particles can also be coated with a suitable additive so as to further improve the respirable fraction.
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