发明授权
US07132445B2 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
有权
3,4-二取代的环丁烯-1,2-二酮作为CXC-趋化因子受体配体
- 专利标题： 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
- 专利标题（中）： 3,4-二取代的环丁烯-1,2-二酮作为CXC-趋化因子受体配体
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申请号： US10630258申请日： 2003-07-30
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公开(公告)号： US07132445B2公开(公告)日： 2006-11-07
- 发明人: Arthur G. Taveras , Cynthia J. Aki , Richard W. Bond , Jianping Chao , Michael Dwyer , Johan A. Ferreira , Jianhua Chao , Younong Yu , John J. Baldwin , Bernd Kaiser , Ge Li , J. Robert Merritt , Purakkattle J. Biju , Kingsley H. Nelson, Jr. , Laura L. Rokosz , James P. Jakway , Gaifa Lai , Minglang Wu , Evan A. Hecker , Daniel Lundell , Jay S. Fine
- 申请人： Arthur G. Taveras , Cynthia J. Aki , Richard W. Bond , Jianping Chao , Michael Dwyer , Johan A. Ferreira , Jianhua Chao , Younong Yu , John J. Baldwin , Bernd Kaiser , Ge Li , J. Robert Merritt , Purakkattle J. Biju , Kingsley H. Nelson, Jr. , Laura L. Rokosz , James P. Jakway , Gaifa Lai , Minglang Wu , Evan A. Hecker , Daniel Lundell , Jay S. Fine
- 申请人地址： US NJ Kenilworth US NJ Cranbury
- 专利权人： Schering Corporation,Pharmacopeia Drug Discovery, Inc.
- 当前专利权人： Schering Corporation,Pharmacopeia Drug Discovery, Inc.
- 当前专利权人地址： US NJ Kenilworth US NJ Cranbury
- 代理商 Henry C. Jeanettte
- 主分类号： A61K31/341
- IPC分类号： A61K31/341 ; A61K31/343 ; A61K31/381 ; C07D333/10 ; C07D33/72
摘要：
There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.
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