- 专利标题： Antisense modulation of stearoyl-CoA desaturase expression
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申请号： US09918187申请日： 2001-07-30
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公开(公告)号： US07132529B2公开(公告)日： 2006-11-07
- 发明人: Rosanne M. Crooke , Mark J. Graham
- 申请人： Rosanne M. Crooke , Mark J. Graham
- 申请人地址： US CA Carlsbad
- 专利权人： Isis Pharmaceuticals, Inc.
- 当前专利权人： Isis Pharmaceuticals, Inc.
- 当前专利权人地址： US CA Carlsbad
- 代理机构： Elmore Patent Law Group, P.C.
- 代理商 Carolyn S. Elmore; Donna T. Ward
- 主分类号： C07H21/04
- IPC分类号： C07H21/04 ; A61K31/70 ; C12Q1/68
摘要：
Antisense compounds, compositions and methods are provided for modulating the expression of stearoyl-CoA desaturase. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding stearoyl-CoA desaturase. Methods of using these compounds for modulation of stearoyl-CoA desaturase expression and for treatment of diseases associated with expression of stearoyl-CoA desaturase are provided.
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